Singapore Institute of Technology
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Intravoxel incoherent motion diffusion-weighted MR imaging: Advancing Medical Image Processing with Machine Learning

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posted on 2025-06-30, 04:24 authored by Cheryl Pei Ling LianCheryl Pei Ling Lian, Eshan Pandey, Xiaomeng Wang, Julian Gan, Ying-Hwey Nai, Thiruneepan SelvakulasingamThiruneepan Selvakulasingam, Ryan Fraser KirwanRyan Fraser Kirwan, Su Lim Forest TanSu Lim Forest Tan, Pek-Lan Khong, Derek Hausenloy
<p dir="ltr">This research study aims to enhance the clinical utility of intravoxel incoherent motion diffusion-weighted magnetic resonance images (IVIM DW-MRI) through deep learning techniques. The objectives were to evaluate the effectiveness of a conditional GAN-based autosegmentation model and an ESRGAN-based image enhancement model in improving segmentation accuracy, image quality, and reliability of quantitative perfusion and diffusion metrics. The findings demonstrated that the autosegmentation model achieved high accuracy (up to 80% Dice coefficient), and the image enhancement model significantly improved diagnostic image quality while maintaining consistency in derived metrics. These results support the potential of machine learning to streamline radiological workflows and advance personalized medicine.</p>

Funding

Academic Research Fund Tier 1 (STEM)

History

Journal/Conference/Book title

Invited Oral presentation, Singapore Society of Radiographers 8th Annual Scientific Meeting, Singapore

Publication date

2025-03-22

Project ID

  • 11682 (R-R12-A404-0002) Improving Magnetic Resonance Image Acquisition and Quality for Disease Assessment

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